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2-(3,5-Dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-one Cas:1044871-04-6 Dehru Stampi
  • 2-(3,5-Dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-one Cas:1044871-04-6

2-(3,5-Dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-one Cas:1044871-04-6

Deskrizzjoni qasira:

Numru tal-Katalgu: XD90961
Cas: 1044871-04-6
Formula Molekulari: C24H29N3O4
Piż Molekulari: 423.5
Disponibbiltà: Fl-istokk
Prezz:  
Ippakkjar minn qabel:  
Pakkett bl-ingrossa: Itlob Kwotazzjoni

 


Dettall tal-Prodott

Tags tal-Prodott

Numru tal-Katalgu XD90961
Isem tal-Prodott 2-(3,5-Dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-one

CAS

 1044871-04-6

Formula Molekulari

 C24H29N3O4

Piż Molekulari

 423.5
Dettalji tal-Ħażna  
Kodiċi tat-Tariffa Armonizzat  

 

Speċifikazzjoni tal-Prodott

Dehra  
Assaġġ  
Bpunt taż-żejt 612.6±65.0 °C (Mbassra)
Densità 1.25±0.1 g/cm3 (Mbassra)
Koeffiċjent tal-aċidità (pKa)9.54±0.20(Mbassra)

 

RVX-297 huwa inibitur BET qawwi ħafna, attiv oralment selettiv għal BD2.L-IC50s ta 'RVX-297 għal BRD2(BD2), BRD3(BD2), u BRD4(BD2) kienu 0.08, 0.05, u 0.02 μM, rispettivament.RVX-297 jinibixxi l-espressjoni ta 'diversi ġeni infjammatorji taċ-ċelluli immuni.Effikaċja ta 'RVX-297 f'mudelli prekliniċi ta' infjammazzjoni akuta u awtoimmunità.

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